No. NEVER use any Safety 1st bed rail on a crib, toddler bed, bunk bed, water bed, or bed with inflatable mattress. Use ONLY on adult bed with mattress and mattress support (boxspring).
The bed rails are suitable for use on beds with mattresses a minimum of 4” (10.2 cm) thick to a maximum of 10” (25.4 cm) thick.
Twin, full, and queen sized mattresses may all be used with these bedrails. They are all protected with a full 36” of length & 8” of height from top of mattress.